The Pharmacokinetics of Chloramphenicol: Understanding How it's Metabolized and Excreted

The Pharmacokinetics of Chloramphenicol: Understanding How it's Metabolized and Excreted

I recently delved into the fascinating topic of the pharmacokinetics of Chloramphenicol, specifically how it's metabolized and excreted in our body. Chloramphenicol, an antibiotic, is absorbed and distributed throughout our body, mainly binding to plasma proteins. It's primarily metabolized in the liver, where it undergoes glucuronidation, converting it into inactive metabolites. These metabolites are then excreted through the kidneys via urine. It's truly amazing to learn about how our body processes this powerful antibiotic and safely eliminates it from our system.